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SCISCIESCOPUS
A Citrus Flavonoid, 6-Demethoxytangeretin, Suppresses Production and Gene Expression of Interleukin-6 in Human Mast Cell-1 via Anaplastic Lymphoma Kinase and Mitogen-Activated Protein Kinase Pathwaysopen access

Kim, Young-Mi; Chae, Hee-Sung; Lee, Eun Joo; Yang, Min Hye; Park, Jin Hee; Yoon, Kee Dong; Kim, Jinwoong; Ahn, Hee Chul; Choi, Young Hee; Chin, Young-Won

ArticleIssue Date2014CitationBIOLOGICAL & PHARMACEUTICAL BULLETIN, v.37, no.5, pp 871 - 876PublisherPHARMACEUTICAL SOC JAPAN
SCIESCOPUS
A stilbene dimer and flavonoids from the aerial parts of Chromolaena odorata with proprotein convertase subtilisin/kexin type 9 expression inhibitory activity

Pel, Pisey; Chae, Hee-Sung; Nhoek, Piseth; Kim, Young-Mi; Khiev, Piseth; Kim, Geum Jin; Nam, Joo-Won; Choi, Hyukjae; Choi, Young Hee; Chin, Young-Won

ArticleIssue Date2020CitationBIOORGANIC CHEMISTRY, v.99PublisherACADEMIC PRESS INC ELSEVIER SCIENCE
SCISCIESCOPUS
alpha-Mangostin ameliorates dextran sulfate sodium -induced colitis through inhibition of NF-kappa B and MAPK pathways

You, Byoung Hoon; Chae, Hee-Sung; Song, Jieun; Ko, Hyuk Wan; Chin, Young-Won; Choi, Young Hee

ArticleIssue Date2017CitationINTERNATIONAL IMMUNOPHARMACOLOGY, v.49, pp 212 - 221PublisherELSEVIER SCIENCE BV
SCISCIESCOPUS
alpha-Mangostin Regulates Hepatic Steatosis and Obesity through SirT1-AMPK and PPAR gamma Pathways in High-Fat Diet-Induced Obese Mice

Choi, Young Hee; Bae, Jin Kyung; Chae, Hee-Sung; Kim, Young-Mi; Sreymom, Yim; Han, Ling; Jang, Ha Young; Chin, Young-Won

ArticleIssue Date2015CitationJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, v.63, no.38, pp 8399 - 8406PublisherAMER CHEMICAL SOC
SCIESCOPUS
Anti-Inflammatory Effects of 6,8-Diprenyl-7,4 '-dihydroxyflavanone from Sophora tonkinensis on Lipopolysaccharide-Stimulated RAW 264.7 Cellsopen access

Chae, Hee-Sung; Yoo, Hunseung; Kim, Young-Mi; Choi, Young Hee; Lee, Chang Hoon; Chin, Young-Won

ArticleIssue Date2016CitationMOLECULES, v.21, no.8PublisherMDPI
SCIESCOPUS
Change of metformin concentrations in the liver as a pharmacological target site of metformin after long-term combined treatment with ginseng berry extractopen access

Lee, Choong Whan; You, Byoung Hoon; Yim, Sreymom; Han, Seung Yon; Chae, Hee-Sung; Bae, Mingoo; Kim, Seo-Yeon; Yu, Jeong-Eun; Jung, Jieun; Nhoek, Piseth, et al.

ArticleIssue Date2023CitationFrontiers in Pharmacology, v.14, pp 01 - 12PublisherFRONTIERS MEDIA SA
SCIESCOPUS
Chemical Constituents from the Roots and Rhizomes of Sophora tonkinensis and Their Effects on Proprotein Convertase Substilisin/Kexin Type 9 Expressionopen access

Pel, Pisey; Chae, Hee-Sung; Nhoek, Piseth; Kim, Young-Mi; An, Chae-Yeong; Yoo, Hunseung; Kang, Minseok; Kim, Hyun Woo; Choi, Young Hee; Chin, Young-Won

ArticleIssue Date2022CitationACS Omega, v.7, no.24, pp 20952 - 20958PublisherAmerican Chemical Society
SCIESCOPUS
Dilignans with a Chromanol Motif Discovered by Molecular Networking from the Stem Barks of Magnolia obovata and Their Proprotein Convertase Subtilisin/Kexin Type 9 Expression Inhibitory Activityopen access

Ahn, Jongmin; Chae, Hee-Sung; Pel, Pisey; Kim, Young-Mi; Choi, Young Hee; Kim, Jinwoong; Chin, Young-Won

ArticleIssue Date2021CitationBIOMOLECULES, v.11, no.3, pp 1 - 14PublisherMDPI
SCIESCOPUS
Discovery of Flavonoids from Scutellaria baicalensis with Inhibitory Activity Against PCSK 9 Expression: Isolation, Synthesis and Their Biological Evaluationopen access

Nhoek, Piseth; Chae, Hee-Sung; Masagalli, Jagadeesh Nagarajappa; Mailar, Karabasappa; Pel, Pisey; Kim, Young-Mi; Choi, Won Jun; Chin, Young-Won

ArticleIssue Date2018CitationMOLECULES, v.23, no.2PublisherMDPI
SCIESCOPUS
Effect of H9, a formula of nine medicinal herbs derived from Osuyubujaijung-tang, on trastuzumab pharmacokinetics in mice

Choi, Young-Hee; Chae, Hee-Sung; Chin, Young-Won

ArticleIssue Date2020CitationFASEB JOURNAL, v.34PublisherWILEY
SCIESCOPUS
Effect of treatment period with LC478, a disubstituted adamantayl derivative, on P-glycoprotein inhibition: its application to increase docetaxel absorption in rats

Han, Seung Yon; Kim, Eun-Sun; You, Byoung Hoon; Chae, Hee-Sung; Lu, Qili; Chin, Young-Won; Ahn, Hee-Chul; Chung, Suk-Jae; Lee, Kyeong; Choi, Young Hee

ArticleIssue Date2020CitationXENOBIOTICA, v.50, no.7, pp 863 - 874PublisherTAYLOR & FRANCIS LTD
SCISCIESCOPUS
Flavonoids and arylbenzofurans from the rhizomes and roots of Sophora tonkinensis with IL-6 production inhibitory activity

Yoo, Hunseung; Chae, Hee-Sung; Kim, Young-Mi; Kang, Minseok; Ryu, Keun Ho; Ahn, Hee Chul; Yoon, Kee Dong; Chin, Young-Won; Kim, Jinwoong

ArticleIssue Date2014CitationBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.24, no.24, pp 5644 - 5647PublisherPERGAMON-ELSEVIER SCIENCE LTD
SCIESCOPUS
Ginseng berry extract enhances metformin efficacy against obesity and hepatic steatosis in mice fed high-fat diet through increase of metformin uptake in liver

Chae, Hee-Sung; You, Byoung Hon; Choi, Junjeong; Chin, Young-Won; Kim, Hojun; Choi, Han Seok; Choi, Young Hee

ArticleIssue Date2019CitationJOURNAL OF FUNCTIONAL FOODS, v.62PublisherELSEVIER
SCIESCOPUS
Identification of neolignans with PCSK9 downregulatory and LDLR upregulatory activities from Penthorum chinense and the potential in cholesterol uptake by transcriptional regulation of LDLR via SREBP2

Chae, Hee-Sung; Pel, Pisey; Cho, Jinwoo; Kim, Young-Mi; An, Chae-Yeong; Huh, Jungmoo; Choi, Young Hee; Kim, Jinwoong; Chin, Young-Won

ArticleIssue Date2021CitationJOURNAL OF ETHNOPHARMACOLOGY, v.278PublisherELSEVIER IRELAND LTD
SCISCIESCOPUS
In Vivo Gastroprotective Effect along with Pharmacokinetics, Tissue Distribution and Metabolism of Isoliquiritigenin in Mice

Choi, Young Hee; Kim, You-Jin; Chae, Hee-Sung; Chin, Young-Won

ArticleIssue Date2015CitationPLANTA MEDICA, v.81, no.7, pp 586 - 593PublisherGEORG THIEME VERLAG KG
SCIESCOPUS
Isolation of polyacetylenes with proprotein convertase/kexin type 9 downregulating activity and two new sesquiterpenes from the aerial parts of Aster koraiensis

Nhoek, Piseth; Ahn, Jongmin; Chae, Hee-Sung; Pel, Pisey; Kim, Young-Mi; Lee, Seung Eun; Lee, Jeong Hoon; Kim, Jinwoong; Choi, Young Hee; Lee, Kyeong, et al.

ArticleIssue Date2020CitationTETRAHEDRON LETTERS, v.61, no.23PublisherPERGAMON-ELSEVIER SCIENCE LTD
SCISCIESCOPUS
Isoliquiritigenin ameliorates dextran sulfate sodium-induced colitis through the inhibition of MAPK pathway

Choi, Young Hee; Bae, Jin-Kyung; Chae, Hee-Sung; Choi, Young Ok; Nhoek, Piseth; Choi, Jong-Sun; Chin, Young-Won

ArticleIssue Date2016CitationINTERNATIONAL IMMUNOPHARMACOLOGY, v.31, pp 223 - 232PublisherELSEVIER
SCISCIESCOPUS
Korean red ginseng extract enhances paclitaxel distribution to mammary tumors and its oral bioavailability by P-glycoprotein inhibition

Bae, Jin Kyung; Kim, You-Jin; Chae, Hee-Sung; Kim, Do Yeun; Choi, Han Seok; Chin, Young-Won; Choi, Young Hee

ArticleIssue Date2017CitationXENOBIOTICA, v.47, no.5, pp 450 - 459PublisherTAYLOR & FRANCIS LTD
SCISCIESCOPUS
Lonicera japonica extract increases metformin distribution in the liver without change of systemic exposed metformin in rats

Han, Seung Yon; Chae, Hee-Sung; You, Byoung Hoon; Chin, Young-Won; Kim, Hojun; Choi, Han Seok; Choi, Young Hee

ArticleIssue Date2019CitationJOURNAL OF ETHNOPHARMACOLOGY, v.238PublisherELSEVIER IRELAND LTD
SCISCIESCOPUS
Maackiapterocarpan B from Sophora tonkinensis Suppresses Inflammatory Mediators via Nuclear Factor-kappa B and Mitogen-Activated Protein Kinase Pathwaysopen access

Chae, Hee-Sung; Yoo, Hunseung; Choi, Young Hee; Choi, Won Jun; Chin, Young-Won

ArticleIssue Date2016CitationBIOLOGICAL & PHARMACEUTICAL BULLETIN, v.39, no.2, pp 259 - 266PublisherPHARMACEUTICAL SOC JAPAN
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