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Bioconversion Products of Whey by Lactic Acid Bacteria Exert Anti-Adipogenic Effect
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Lee, Ji Soo | - |
| dc.contributor.author | Hyun, In Kyung | - |
| dc.contributor.author | Yoon, Ji-Won | - |
| dc.contributor.author | Seo, Hye-Jin | - |
| dc.contributor.author | Kang, Seok-Seong | - |
| dc.date.accessioned | 2023-04-27T19:41:02Z | - |
| dc.date.available | 2023-04-27T19:41:02Z | - |
| dc.date.issued | 2021 | - |
| dc.identifier.issn | 2636-0772 | - |
| dc.identifier.issn | 2636-0780 | - |
| dc.identifier.uri | https://scholarworks.dongguk.edu/handle/sw.dongguk/5655 | - |
| dc.description.abstract | Microbial bioconversion using lactic acid bacteria (LAB) provides several human health benefits. Although whey and whey-derived bioactive compounds can contribute to an improvement in human health, the potential anti-obesity effect of whey bioconversion by LAB has not been well studied. This study aimed to investigate whether bioconversion of whey by Pediococcus pentosaceus KI31 and Lactobacillus sakei KI36 (KI31-W and KI36-W, respectively) inhibits 3T3-L1 preadipocyte differentiation. Both KI31-W and KI36-W reduced intracellular lipid accumulation significantly, without decreasing 3T3-L1 preadipocyte proliferation. In addition, obesity-related transcription factor (peroxisome proliferator-activated receptor.) and genes (adipocyte fatty acid-binding protein and lipoprotein lipase) were down-regulated significantly in 3T3-L1 cells in the presence of KI31-W and KI36-W. Collectively, these results suggest that bioconversion of whey by LAB exhibits anti-adipogenic activity and may be applied as a therapeutic agent for obesity. | - |
| dc.format.extent | 8 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | KOREAN SOC FOOD SCIENCE ANIMAL RESOURCES | - |
| dc.title | Bioconversion Products of Whey by Lactic Acid Bacteria Exert Anti-Adipogenic Effect | - |
| dc.type | Article | - |
| dc.publisher.location | 대한민국 | - |
| dc.identifier.doi | 10.5851/kosfa.2020.e78 | - |
| dc.identifier.scopusid | 2-s2.0-85099687003 | - |
| dc.identifier.wosid | 000605455200013 | - |
| dc.identifier.bibliographicCitation | FOOD SCIENCE OF ANIMAL RESOURCES, v.41, no.1, pp 145 - 152 | - |
| dc.citation.title | FOOD SCIENCE OF ANIMAL RESOURCES | - |
| dc.citation.volume | 41 | - |
| dc.citation.number | 1 | - |
| dc.citation.startPage | 145 | - |
| dc.citation.endPage | 152 | - |
| dc.type.docType | Article | - |
| dc.identifier.kciid | ART002663246 | - |
| dc.description.isOpenAccess | Y | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.description.journalRegisteredClass | kci | - |
| dc.relation.journalResearchArea | Food Science & Technology | - |
| dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
| dc.subject.keywordAuthor | bioconversion | - |
| dc.subject.keywordAuthor | whey | - |
| dc.subject.keywordAuthor | lactic acid bacteria | - |
| dc.subject.keywordAuthor | obesity | - |
| dc.subject.keywordAuthor | 3T3-L1 preadipocyte | - |
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Related Researcher
- Kang, Seok Seong
- College of Life Science and Biotechnology (식품바이오융합공학과)