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Cited 22 time in webofscience Cited 30 time in scopus
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Biopolymer film fabrication for skin mimetic tissue regenerative wound dressing applications

Authors
Sellappan, Logesh KumarAnandhavelu, SanmugamDoble, MukeshPerumal, GovindarajJeon, Ji-HoonVikraman, DhanasekaranKim, Hyun-Seok
Issue Date
Feb-2022
Publisher
Taylor & Francis
Keywords
Biopolymer; biowaste; fibrin; keratin; Teflon; wound dressing
Citation
International Journal of Polymeric Materials and Polymeric Biomaterials, v.71, no.3, pp 196 - 207
Pages
12
Indexed
SCIE
SCOPUS
Journal Title
International Journal of Polymeric Materials and Polymeric Biomaterials
Volume
71
Number
3
Start Page
196
End Page
207
URI
https://scholarworks.dongguk.edu/handle/sw.dongguk/3575
DOI
10.1080/00914037.2020.1817019
ISSN
0091-4037
1563-535X
Abstract
A biopolymer film serving as a wound-healing substitute was fabricated using keratin and fibrin (extracted from a goat hoof and blood, respectively) via modified Shindai techniques. The importance of keratin and fibrin along with gelatin and mupirocin for the fabrication of a biofilm by solvent casting method is shown in this work.In vitromicroscopic images of the fibroblast NIH 3T3 cell lines revealed the biocompatibility, cell viability, cell adhesion, and proliferation of biopolymer film in the wound site. The low-cost and biowaste-source-extracted keratin and fibrin blended biopolymer film supports the wound-healing process in humans.
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