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Corilagin with inhibitory activity against NO production from Euphorbia supina
- Authors
- Chae, H.-S.; Kim, Y.-M.; Lee, E.J.; Song, H.H.; Oh, S.-R.; Choi, Y.H.; Chin, Y.-W.
- Issue Date
- 2014
- Publisher
- Korean Society of Pharmacognosy
- Keywords
- Corilagin; Euphorbia supina; Euphorbiaceae; Nitric oxide; Tannin
- Citation
- Natural Product Sciences, v.20, no.2, pp 126 - 129
- Pages
- 4
- Indexed
- SCOPUS
KCI
- Journal Title
- Natural Product Sciences
- Volume
- 20
- Number
- 2
- Start Page
- 126
- End Page
- 129
- ISSN
- 1226-3907
- Abstract
- Bioactivity-guided investigation on whole plant of Euphorbia supina, using LPS-induced Raw264.7 cells, led to the identificaiton of a tannin which was not reported from this plant along with four known constituents (quercetin, astragalin, juglanin and methyl gallate). The structure of the tannin was determined as corilagin by the interpretation of NMR (1D and 2D) and MS spectroscopic data. All the isolates were tested for the inhibitory activity against NO production in LPS-induced Raw264.7 cells. Among the tested isolates, corilagin was found to be the most active compound. © 2014, Korean Society of Pharmacognosy. All right reserved.
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Related Researcher
- Choi, Young Hee
- College of Pharmacy (Department of Pharmacy)