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Cited 20 time in webofscience Cited 19 time in scopus
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Electrophoretic pattern of glutathione S-transferase (GST) in antibiotic resistance Gram-positive bacteria from poultry litter

Authors
Pugazhendhi, ArivalaganDhanarani, SrideviShankar, CongeevaramPrakash, PiruthivirajRanganathan, KuppusamySaratale, Rijuta GaneshThamaraiselvi, Kaliannan
Issue Date
Sep-2017
Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
Keywords
Glutathione S-transferase (GST); Antibiotics Poultry litter; Isozyme; Resistant bacteria
Citation
MICROBIAL PATHOGENESIS, v.110, pp 285 - 290
Pages
6
Indexed
SCI
SCIE
SCOPUS
Journal Title
MICROBIAL PATHOGENESIS
Volume
110
Start Page
285
End Page
290
URI
https://scholarworks.dongguk.edu/handle/sw.dongguk/23817
DOI
10.1016/j.micpath.2017.07.003
ISSN
0882-4010
1096-1208
Abstract
The present study is aimed to assess the role of glutathione S-transferase (GST) in antibiotic resistance among the bacteria isolated from the poultry litter and to identify the effect of GST to reduce the antimicrobial activity of antibiotics. Induction of various antibiotics to Staphylococcus, Streptococcus and Micrococcus sp. isolated from the poultry litter showed that the activity of GST was three to four folds higher than those of control. Analysis of the isozyme pattern of GST revealed that variation in the expression may be due to antibiotic resistance. The results concluded that GST might play an important role in the protection against the toxic effect of the antimicrobial agents which leads bacteria to become resistant to antibiotics. (C) 2017 Elsevier Ltd. All rights reserved.
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