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Stem cell responses to nanotopography
- Authors
- Park, Siyeon; Im, Gun-Il
- Issue Date
- Mar-2015
- Publisher
- WILEY
- Keywords
- nanotopography; musculoskeletal regeneration; stem cells
- Citation
- JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, v.103, no.3, pp 1238 - 1245
- Pages
- 8
- Indexed
- SCI
SCIE
SCOPUS
- Journal Title
- JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Volume
- 103
- Number
- 3
- Start Page
- 1238
- End Page
- 1245
- ISSN
- 1549-3296
1552-4965
- Abstract
- Cells interact with various nanoscaled topographical and biochemical cues in their cellular macromolecular environment. Nanotopography recreates or mimic the cellular macromolecular environment in vitro. The influence of material surface topography on the behavior of adherent cells has been studied. Current techniques enable various kinds of nanopatterned surface to be generated and applied to cells. The purpose of this review is to provide an overview of nanotopography and its surface patterns, and introduce nanotopography effects on cell behavior including cell attachment, proliferation, and cell differentiation with particular emphasis on musculoskeletal regeneration. (c) 2014 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 103A: 1238-1245, 2015.
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Related Researcher
- Im, Gun Il
- Graduate School (Department of Medicine)