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Showing results 1 to 19 of 19

SCISCIESCOPUS
A novel antitumor piperazine alkyl compound causes apoptosis by inducing RhoB expression via ROS-mediated c-Abl/p38 MAPK signaling

Chung, Kyung-Sook; Han, Gyoonhee; Kim, Bo-Kyung; Kim, Hwan-Mook; Yang, Jee Sun; Ahn, Jiwon; Lee, Kyeong; Song, Kyung-Bin; Won, Misun

ArticleIssue Date2013CitationCANCER CHEMOTHERAPY AND PHARMACOLOGY, v.72, no.6, pp 1315 - 1324PublisherSPRINGER
SCIESCOPUS
A Novel Malate Dehydrogenase 2 Inhibitor Suppresses Hypoxia-Inducible Factor-1 by Regulating Mitochondrial Respirationopen access

Ban, Hyun Seung; Xu, Xuezhen; Jang, Kusik; Kim, Inhyub; Kim, Bo-Kyung; Lee, Kyeong; Won, Misun

ArticleIssue Date2016CitationPLOS ONE, v.11, no.9PublisherPUBLIC LIBRARY SCIENCE
SCISCIESCOPUS
Bcl-2-dependent synthetic lethal interaction of the IDF-11774 with the V0 subunit C of vacuolar ATPase (ATP6V0C) in colorectal canceropen access

Kim, Bo-Kyung; Nam, Soon Woo; Min, Byung Soh; Ban, Hyun Seung; Paik, Soonmyung; Lee, Kyeong; Im, Joo-Young; Lee, Youngjoo; Park, Joon-Tae; Kim, Seon-Young, et al.

ArticleIssue Date2018CitationBRITISH JOURNAL OF CANCER, v.119, no.11, pp 1347 - 1357PublisherNATURE PUBLISHING GROUP
SCISCIESCOPUS
Design, synthesis and biological evaluation of novel aliphatic amido/sulfonamido-quaternary ammonium salts as antitumor agents

Song, Doona; Yang, Jee Sun; Kim, Seo Joong; Kim, Bo-Kyung; Park, Song-Kyu; Won, Misun; Lee, Kiho; Kim, Hwan Mook; Choi, Kang-Yell; Lee, Kyeong, et al.

ArticleIssue Date2013CitationBIOORGANIC & MEDICINAL CHEMISTRY, v.21, no.3, pp 788 - 794PublisherPERGAMON-ELSEVIER SCIENCE LTD
SCIESCOPUS
Design, Synthesis and Biological Evaluation of Novel MDH Inhibitors Targeting Tumor Microenvironmentopen access

Godesi, Sreenivasulu; Han, Jeong-Ran; Kim, Jang-Keun; Kwak, Dong-Ik; Lee, Joohan; Nada, Hossam; Kim, Minkyoung; Yang, Hyun-A; Im, Joo-Young; Ban, Hyun Seung, et al.

ArticleIssue Date2023CitationPharmaceuticals, v.16, no.5, pp 1 - 35PublisherMDPI
SCIESCOPUSKCI
DGG-100629 inhibits lung cancer growth by suppressing the NFATc1/DDIAS/STAT3 pathwayopen access

Im, Joo-Young; Kim, Bo-Kyung; Yoon, Sung-Hoon; Cho, Byoung Chul; Baek, Yu Mi; Kang, Mi-Jung; Kim, Nayeon; Gong, Young-Dae; Won, Misun

ArticleIssue Date2021CitationEXPERIMENTAL AND MOLECULAR MEDICINE, v.53, no.4, pp 643 - 653PublisherSPRINGERNATURE
SCISCIESCOPUS
Identification of Malate Dehydrogenase 2 as a Target Protein of the HIF-1 Inhibitor LW6 using Chemical Probes

Lee, Kyeong; Ban, Hyun Seung; Naik, Ravi; Hong, Ye Seul; Son, Seohyun; Kim, Bo-Kyung; Xia, Yan; Song, Kyung Bin; Lee, Hong-Sub; Won, Misun

ArticleIssue Date2013CitationANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.52, no.39, pp 10286 - 10289PublisherWILEY-V C H VERLAG GMBH
SCISCIESCOPUS
Identification of Targets of the HIF-1 Inhibitor IDF-11774 Using Alkyne-Conjugated Photoaffinity Probes

Ban, Hyun Seung; Naik, Ravi; Kim, Hwan Mook; Kim, Bo-Kyung; Lee, Hongsub; Kim, Inhyub; Ahn, Heechul; Jang, Yerin; Jang, Kyusik; Eo, Yumi, et al.

ArticleIssue Date2016CitationBIOCONJUGATE CHEMISTRY, v.27, no.8, pp 1911 - 1920PublisherAMER CHEMICAL SOC
SCIESCOPUS
LW1497, an Inhibitor of Malate Dehydrogenase, Suppresses TGF-beta 1-Induced Epithelial-Mesenchymal Transition in Lung Cancer Cells by Downregulating Slugopen access

Kim, Hyun Ji; Park, Mi Kyung; Byun, Hyun Jung; Kim, Minkyoung; Kim, Boram; Yu, Lu; Nguyen, Tuan Minh; Ha Nguyen, Thi; Do, Phuong Anh; Kim, Eun Ji, et al.

ArticleIssue Date2021CitationANTIOXIDANTS, v.10, no.11PublisherMDPI
SCISCIESCOPUS
Methyl 3-(3-(4-(2,4,4-Trimethylpentan-2-yl)phenoxy)-propanamido)benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism

Naik, Ravi; Ban, Hyun Seung; Jang, Kyusic; Kim, Inhyub; Xu, Xuezhen; Harmalkar, Dipesh; Shin, Seong-Ah; Kim, Minkyoung; Kim, Bo-Kyung; Park, Jaehyung, et al.

ArticleIssue Date2017CitationJOURNAL OF MEDICINAL CHEMISTRY, v.60, no.20, pp 8631 - 8646PublisherAMER CHEMICAL SOC
SCISCIESCOPUS
NSC126188 induces apoptosis of prostate cancer PC-3 cells through inhibition of Akt membrane translocation, FoxO3a activation, and RhoB transcription

Won, Kyoung-Jae; Kim, Bo Kyung; Han, Gyoonhee; Lee, Kyeong; Jung, Young-Jin; Kim, Hwan-Mook; Song, Kyung Bin; Chung, Kyung-Sook; Won, Misun

ArticleIssue Date2014CitationAPOPTOSIS, v.19, no.1, pp 179 - 190PublisherSPRINGER
SCISCIESCOPUS
p300 cooperates with c-Jun and PARP-1 at the p300 binding site to activate RhoB transcription in NSC126188-mediated apoptosis

Kim, Bo-Kyung; Im, Joo-Young; Han, Gyoonhee; Lee, Woo-Jung; Won, Kyoung-Jae; Chung, Kyung-Sook; Lee, Kyeong; Ban, Hyun Seung; Song, KyungBin; Won, Misun

ArticleIssue Date2014CitationBIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, v.1839, no.5, pp 364 - 373PublisherELSEVIER SCIENCE BV
SCIESCOPUS
Quinoxaline-based UCHL5 inhibitor as a next-generation proteasome-targeting anticancer agent beyond 20S inhibitionopen access

Han, Tae-Hee; Lee, Joohan; Im, Joo-Young; Nada, Hossam; Godesi, Sreenivasulu; Kim, Changseong; Seo, Areum; Hwang, Inseo; Shin, Seong-Ah; Lee, Ga Seul, et al.

ArticleIssue Date2026CitationJournal of Advanced ResearchPublisherElsevier B.V.
SCISCIESCOPUS
Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21(Cip1) downregulation are required for shikonin-induced apoptosis

Ahn, Jiwon; Won, Misun; Choi, Jeong-Hae; Kim, Yong Sung; Jung, Cho-Rock; Im, Dong-Su; Kyun, Mi-Lang; Lee, Kyeong; Song, Kyung-Bin; Chung, Kyung-Sook

ArticleIssue Date2013CitationAPOPTOSIS, v.18, no.7, pp 870 - 881PublisherSPRINGER
SCIESCOPUS
Stilbenoid derivatives as potent inhibitors of HIF-1α-centric cancer metabolism under hypoxiaopen access

Han, Tae-Hee; Lee, Joohan; Harmalkar, Dipesh S.; Kang, Hyeseul; Jin, Guanghai; Park, Min Kyung; Kim, Minkyoung; Yang, Hyun-A; Kim, Jinsu; Kwon, Su Jeong, et al.

ArticleIssue Date2024CitationBiomedicine and Pharmacotherapy, v.176, pp 1 - 17PublisherElsevier Masson SAS
SCISCIESCOPUS
Synthesis and biological evaluation of novel aliphatic amido-quaternary ammonium salts for anticancer chemotherapy: Part II

Yang, Jee Sun; Song, Doona; Ko, Won Jin; Kim, Bunyea; Kim, Bo-Kyung; Park, Song-Kyu; Won, Misun; Lee, Kiho; Lee, Kyeong; Kim, Hwan Mook, et al.

ArticleIssue Date2013CitationEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v.63, pp 621 - 628PublisherELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
SCISCIESCOPUS
Synthesis and Structure-Activity Relationship Study of Chemical Probes as Hypoxia Induced Factor-1 alpha/Malate Dehydrogenase 2 Inhibitors

Naik, Ravi; Won, Misun; Ban, Hyun Seung; Bhattarai, Deepak; Xu, Xuezhen; Eo, Yumi; Hong, Ye Seul; Singh, Sarbjit; Choi, Yongseok; Ahn, Hee-Chul, et al.

ArticleIssue Date2014CitationJOURNAL OF MEDICINAL CHEMISTRY, v.57, no.22, pp 9522 - 9538PublisherAMER CHEMICAL SOC
SCIESCOPUSKCI
The disubstituted adamantyl derivative LW1564 inhibits the growth of cancer cells by targeting mitochondrial respiration and reducing hypoxia-inducible factor (HIF)-1 alpha accumulationopen access

Kim, Inhyub; Kim, Minkyoung; Park, Min Kyung; Naik, Ravi; Park, Jae Hyung; Kim, Bo-Kyung; Choi, Yongseok; Chang, Kwan Young; Won, Misun; Ban, Hyun Seung, et al.

ArticleIssue Date2020CitationEXPERIMENTAL AND MOLECULAR MEDICINE, v.52, no.11, pp 1845 - 1856PublisherSPRINGERNATURE
SCIESCOPUS
The novel hypoxia-inducible factor-1 alpha inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growthopen access

Ban, Hyun Seung; Kim, Bo-Kyung; Lee, Hongsub; Kim, Hwan Mook; Harmalkar, Dipesh; Nam, Miso; Park, Song-Kyu; Lee, Kiho; Park, Joon-Tae; Kim, Inhyub, et al.

ArticleIssue Date2017CitationCELL DEATH & DISEASE, v.8, no.6PublisherNATURE PUBLISHING GROUP
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