The crystal structure of a natural DNA polymerase complexed with mirror DNA

  • An, Jinsu; 
  • Choi, Jaewoo; 
  • Hwang, Dohyeon; 
  • Park, Jihyun; 
  • Pemble, Charles W.; 
  • ... Ahn, Heechul; 
  • 외 4명
Citations

WEB OF SCIENCE

11
Citations

SCOPUS

11

초록

The intrinsic l-DNA binding properties of a natural DNA polymerase was discovered. The binding affinity of Dpo4 polymerase for l-DNA was comparable to that for d-DNA. The crystal structure of Dpo4/l-DNA complex revealed a dimer formed by the little finger domain that provides a binding site for l-DNA.

키워드

DELIVERY; NANOSTRUCTURES; REPLICATION; SPIEGELMER; MECHANISM; FIDELITY; SYSTEM
제목
The crystal structure of a natural DNA polymerase complexed with mirror DNA
저자
An, Jinsu; Choi, Jaewoo; Hwang, Dohyeon; Park, Jihyun; Pemble, Charles W.; Thi Hoai Men Duong; Kim, Kyoung-Ran; Ahn, Heechul; Chung, Hak Suk; Ahn, Dae-Ro
DOI
10.1039/c9cc09351f
발행일
2020-02-18
유형
Article
저널명
Chemical Communications
권
56
호
14
페이지
2186 ~ 2189