Enhancement of antioxidant activities and stabilities of quercetin and isoquercetin through the combination of nanoencapsulation and hydrogel incorporation
  • Kang, Min Je
  • Kim, Do-Yeong
  • Baek, Youjin
  • Lee, Hyeon Gyu
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초록

This study investigated the possibility of improving the antioxidant activities and solubilities of quercetin (QUE) and isoquercetin (IQUE) through a combination of nanoencapsulation with gel incorporation. QUE- and IQUEloaded nanoparticles (QUE and IQUE NPs, respectively) were prepared through ionic gelation between chitooligosaccharide and poly-& gamma;-glutamic acid. The antioxidant activities of QUE and IQUE increased by 2.5 and 3.5 times, respectively, after nanoencapsulation. Furthermore, QUE and IQUE NP-filled gelatin gels (G-QUE and GIQUE NPs, respectively) showed higher antioxidant stabilities than QUE and IQUE NPs, respectively. G-QUE and G-IQUE NPs exhibited significantly (p < 0.05) higher G' values than free QUE and IQUE in gels, respectively. Moreover, the hardness of G-QUE NPs was significantly (p < 0.05) higher than that of free QUE in gel. In conclusion, combining nanoencapsulation and gel incorporation can improve the antioxidant activities, stabilities, and physical properties of QUE and IQUE.

키워드

NanoencapsulationAntioxidant activityQuercetinIsoquercetinRheological propertyGAMMA-GLUTAMIC ACIDBIOLOGICAL-ACTIVITIESOXIDATIVE STRESSRED WINECHITOSANNANOPARTICLESGELATINFOODBIOAVAILABILITYDERIVATIVES
제목
Enhancement of antioxidant activities and stabilities of quercetin and isoquercetin through the combination of nanoencapsulation and hydrogel incorporation
저자
Kang, Min JeKim, Do-YeongBaek, YoujinLee, Hyeon Gyu
DOI
10.1016/j.fbio.2023.102963
발행일
2023-10
유형
Article
저널명
Food Bioscience
55
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1 ~ 8