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Recent Advances in Anticancer Chemotherapeutics based upon Azepine Scaffold
- Singh, Sarbjit;
- Goo, Jail;
- Gajulapati, Veeraswamy;
- Chang, Tong-Shin;
- Lee, Kyeong;
- 외 1명
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16초록
In the recent few years, the emergence of heterocyclic ring-containing anti-cancer agents has gained a great deal of attention among medicinal chemists. Among these, azepine-based compounds are particularly becoming attractive recently. In this Focus Review, we highlight the recent advancements in the development of azepine-based anti-cancer compounds since the year 2000.
키워드
Anticancer agents; azepane scaffold; chemotherapeutics; histone deacetylases; kinase inhibitors; tubulin inhibitors; phototherapeutic agents; hormone modulators; GERANYLGERANYLTRANSFERASE-I INHIBITORS; NUCLEOSOME CORE PARTICLE; STRUCTURE-BASED DESIGN; P-GLYCOPROTEIN; 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE; PROTEASOME INHIBITORS; BIOLOGICAL EVALUATION; DERIVATIVES BEARING; RECENT PROGRESS; CELL LINES
- 제목
- Recent Advances in Anticancer Chemotherapeutics based upon Azepine Scaffold
- 저자
- Singh, Sarbjit; Goo, Jail; Gajulapati, Veeraswamy; Chang, Tong-Shin; Lee, Kyeong; Choi, Yongseok
- 발행일
- 2016-05-01
- 유형
- Article
- 권
- 16
- 호
- 5
- 페이지
- 539 ~ 557