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Chimeric crRNAs Retaining Activity of Cas12a with Potential to Improve Specificity

Park, Jihyun;
Choi, Jaewoo;
Men Thi Hoai Duong;
Ahn, Hee-Chul;
Hong, Seung Woo;
외 4명

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SCOPUS

1

초록

RNA residues in the guide region of crRNA for Cas12a can be partially replaced by DNA.

키워드

CRISPR-Cas; Cas12a; Chimeric crRNA; CRISPR; CPF1; SYSTEM; ENDONUCLEASE; COMPLEX

제목: Chimeric crRNAs Retaining Activity of Cas12a with Potential to Improve Specificity

저자: Park, Jihyun; Choi, Jaewoo; Men Thi Hoai Duong; Ahn, Hee-Chul; Hong, Seung Woo; Hwang, Gil Tae; An, Jinsu; Chung, Hak Suk; Ahn, Dae-Ro

DOI: 10.1002/bkcs.12109

발행일: 2021-01

유형: Article

저널명: Bulletin of the Korean Chemical Society

권: 42

호: 1

페이지: 87 ~ 90

언어: ENG

출판사: WILEY-V C H VERLAG GMBH

발행국가: 독일

분량: 4 페이지

ISSN: E 1229-5949
P 0253-2964