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Reversal of Epithelial-Mesenchymal Transition by Natural Anti-Inflammatory and Pro-Resolving Lipids
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29초록
Epithelial mesenchymal transition (EMT) is a key process in the progression of malignant cancer. Therefore, blocking the EMT can be a critical fast track for the development of anticancer drugs. In this paper, we update recent research output of EMT and we explore suppression of EMT by natural anti-inflammatory compounds and pro-resolving lipids.
키워드
epithelial mesenchymal transition; inflammation; malignant cancer; natural anti-inflammatory compounds; pro-resolving lipids; NF-KAPPA-B; BREAST-CANCER CELLS; TUMOR-NECROSIS-FACTOR; HUMAN LUNG-CANCER; HEPATOCELLULAR-CARCINOMA CELLS; EPIDERMAL-GROWTH-FACTOR; PANCREATIC-CANCER; TGF-BETA; COLORECTAL-CANCER; SIGNALING PATHWAY
- 제목
- Reversal of Epithelial-Mesenchymal Transition by Natural Anti-Inflammatory and Pro-Resolving Lipids
- 저자
- Lee, Chang Hoon
- 발행일
- 2019-12
- 유형
- Review
- 저널명
- Cancers
- 권
- 11
- 호
- 12