Reversal of Epithelial-Mesenchymal Transition by Natural Anti-Inflammatory and Pro-Resolving Lipids

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25
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SCOPUS

30

초록

Epithelial mesenchymal transition (EMT) is a key process in the progression of malignant cancer. Therefore, blocking the EMT can be a critical fast track for the development of anticancer drugs. In this paper, we update recent research output of EMT and we explore suppression of EMT by natural anti-inflammatory compounds and pro-resolving lipids.

키워드

epithelial mesenchymal transition; inflammation; malignant cancer; natural anti-inflammatory compounds; pro-resolving lipids; NF-KAPPA-B; BREAST-CANCER CELLS; TUMOR-NECROSIS-FACTOR; HUMAN LUNG-CANCER; HEPATOCELLULAR-CARCINOMA CELLS; EPIDERMAL-GROWTH-FACTOR; PANCREATIC-CANCER; TGF-BETA; COLORECTAL-CANCER; SIGNALING PATHWAY
제목
Reversal of Epithelial-Mesenchymal Transition by Natural Anti-Inflammatory and Pro-Resolving Lipids
저자
Lee, Chang Hoon
DOI
10.3390/cancers11121841
발행일
2019-12
유형
Review
저널명
Cancers
권
11
호
12