Electrophoretic pattern of glutathione S-transferase (GST) in antibiotic resistance Gram-positive bacteria from poultry litter

Pugazhendhi, Arivalagan; Dhanarani, Sridevi; Shankar, Congeevaram; Prakash, Piruthiviraj; Ranganathan, Kuppusamy; Saratale, Rijuta Ganesh; Thamaraiselvi, Kaliannan

doi:10.1016/j.micpath.2017.07.003

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Electrophoretic pattern of glutathione S-transferase (GST) in antibiotic resistance Gram-positive bacteria from poultry litter

Pugazhendhi, Arivalagan;
Dhanarani, Sridevi;
Shankar, Congeevaram;
Prakash, Piruthiviraj;
Ranganathan, Kuppusamy;
외 2명

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초록

The present study is aimed to assess the role of glutathione S-transferase (GST) in antibiotic resistance among the bacteria isolated from the poultry litter and to identify the effect of GST to reduce the antimicrobial activity of antibiotics. Induction of various antibiotics to Staphylococcus, Streptococcus and Micrococcus sp. isolated from the poultry litter showed that the activity of GST was three to four folds higher than those of control. Analysis of the isozyme pattern of GST revealed that variation in the expression may be due to antibiotic resistance. The results concluded that GST might play an important role in the protection against the toxic effect of the antimicrobial agents which leads bacteria to become resistant to antibiotics. (C) 2017 Elsevier Ltd. All rights reserved.

키워드

Glutathione S-transferase (GST); Antibiotics Poultry litter; Isozyme; Resistant bacteria; PROTEIN; PURIFICATION; ISOENZYMES; IDENTIFICATION; EXPRESSION; ENZYMES; STRESS

제목: Electrophoretic pattern of glutathione S-transferase (GST) in antibiotic resistance Gram-positive bacteria from poultry litter

저자: Pugazhendhi, Arivalagan; Dhanarani, Sridevi; Shankar, Congeevaram; Prakash, Piruthiviraj; Ranganathan, Kuppusamy; Saratale, Rijuta Ganesh; Thamaraiselvi, Kaliannan

DOI: 10.1016/j.micpath.2017.07.003

발행일: 2017-09

유형: Article

저널명: Microbial Pathogenesis

권: 110

페이지: 285 ~ 290