Genetically engineered bacteriophages as novel nanomaterials: applications beyond antimicrobial agents
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8
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10

초록

Bacteriophages, also known as phages, are viruses that replicate in bacteria and archaea. Phages were initially discovered as antimicrobial agents, and they have been used as therapeutic agents for bacterial infection in a process known as "phage therapy." Recently, phages have been investigated as functional nanomaterials in a variety of areas, as they can function not only as therapeutic agents but also as biosensors and tissue regenerative materials. Phages are nontoxic to humans, and they possess self-assembled nanostructures and functional properties. Additionally, phages can be easily genetically modified to display specific peptides or to screen for functional peptides via phage display. Here, we demonstrated the application of phage nanomaterials in the context of tissue engineering, sensing, and probing.

키워드

bacteriophagenanomaterialbiosensortissue regenerationgenetic engineeringfilamentous phageM13phage displayPHAGE-DISPLAYM13 BACTERIOPHAGEFILAMENTOUS BACTERIOPHAGECANCER-PATIENTSRANDOM PEPTIDETHERAPYPURIFICATIONIDENTIFICATIONNANOPARTICLESVECTORS
제목
Genetically engineered bacteriophages as novel nanomaterials: applications beyond antimicrobial agents
저자
Kim, Seong-MinHeo, Hye RyoungKim, Chang SupShin, Hwa Hui
DOI
10.3389/fbioe.2024.1319830
발행일
2024-04
유형
Review
저널명
Frontiers in Bioengineering and Biotechnology
12
페이지
01 ~ 18