New RNA Purine Building Blocks, 4-Selenopurine Nucleosides: First Synthesis and Unusual Mixture of Sugar Puckerings

Yu, Jinha; Kim, Jin-Hee; Lee, Hyuk Woo; Alexander, Varughese; Ahn, Hee-Chul; Choi, Won Jun; Choi, Jungwon; Jeong, Lak Shin

doi:10.1002/chem.201300741

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New RNA Purine Building Blocks, 4-Selenopurine Nucleosides: First Synthesis and Unusual Mixture of Sugar Puckerings

Yu, Jinha;
Kim, Jin-Hee;
Lee, Hyuk Woo;
Alexander, Varughese;
Ahn, Hee-Chul;
... Choi, Won Jun;
외 2명

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초록

Writer's blocks: The first synthesis of RNA purine building blocks, 4'-selenoadenosine and 4'-selenoguanosine was achieved from D-ribose by regioisomeric rearrangement, which was confirmed by X-ray crystallography. 4'-Selenoadenosine exists in an unusual mixture of north and south conformers in the solid state. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

키워드

nucleic acids; nucleosides; RNA; selenonucleosides; X-ray crystallography; ADENOSYL-L-HOMOCYSTEINE; STEREOSELECTIVE-SYNTHESIS; HIV

제목: New RNA Purine Building Blocks, 4-Selenopurine Nucleosides: First Synthesis and Unusual Mixture of Sugar Puckerings

저자: Yu, Jinha; Kim, Jin-Hee; Lee, Hyuk Woo; Alexander, Varughese; Ahn, Hee-Chul; Choi, Won Jun; Choi, Jungwon; Jeong, Lak Shin

DOI: 10.1002/chem.201300741

발행일: 2013-04

유형: Article

저널명: Chemistry - A European Journal

권: 19

호: 18

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