Nucleosides with Modified Sugar Ring: Synthesis and Biological Activities

  • Singh, Sarbjit
  • Bhattarai, Deepak
  • Veeraswamy, Gajulapati
  • Choi, Yongseok
  • Lee, Kyeong
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초록

In the recent few years, the emergence of nucleosides containing modified sugar ring or modified base moiety has gained much attention due to their enhanced biological activities as compared to parent nucleosides containing 5-carbon ribose or deoxyribose sugar ring. In this review, we highlight the recent advances in synthesis and biological activities of nucleosides containing modified sugar rings reported between years 2010 to 2015.

키워드

Functionalized nucleosidesmodified nucleosidesfluorinated nucleosidesselenonucleosidesthionucleosidesbiologically active nucleosidesPOTENT ANTIVIRAL AGENTSS-ADENOSYLHOMOCYSTEINE HYDROLASEPHOSPHONIC ACID NUCLEOSIDES3,4-DIMETHOXYBENZYL PROTECTING GROUPSL-CYCLOPENTENONE DERIVATIVESA(3) ADENOSINE RECEPTORHERPES-SIMPLEX-VIRUSANTI-HIV ACTIVITYCARBOCYCLIC 2'-OXA-3'-AZANUCLEOSIDESPYRIMIDINE PYRANONUCLEOSIDES
제목
Nucleosides with Modified Sugar Ring: Synthesis and Biological Activities
저자
Singh, SarbjitBhattarai, DeepakVeeraswamy, GajulapatiChoi, YongseokLee, Kyeong
DOI
10.2174/1385272819666150803235458
발행일
2016-04-01
유형
Article
저널명
Current Organic Chemistry
20
8
페이지
856 ~ 897