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Alpha-mangostin에 의한 Arginine-132이 Histidine으로 돌연변이가 일어난 Isocitrate Dehydrogenase-1 (IDH1-R132H) 단백질의 활성 억제 효과
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | 금영삼 | - |
| dc.contributor.author | 김효준 | - |
| dc.contributor.author | 이경 | - |
| dc.contributor.author | 진영원 | - |
| dc.date.accessioned | 2025-09-09T08:04:28Z | - |
| dc.date.available | 2025-09-09T08:04:28Z | - |
| dc.identifier.uri | https://scholarworks.dongguk.edu/handle/sw.dongguk/60198 | - |
| dc.description.abstract | 본 연구진은 천연물에서 IDH1-R132H 단백질의 저해제 검색을 통하여 alpha-mangostin이 IDH1 단백질의 활성은 영향을 주지 않고 IDH1-R132H 단백질의 효능만을 억제하는 새로운 저해제 임을 밝혀 내었다. | - |
| dc.title | Alpha-mangostin에 의한 Arginine-132이 Histidine으로 돌연변이가 일어난 Isocitrate Dehydrogenase-1 (IDH1-R132H) 단백질의 활성 억제 효과 | - |
| dc.title.alternative | PHAMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING GLIOMA COMPRISING ALPHA-MANGOSTIN AS A EFFECTIVE COMPONENT | - |
| dc.type | Patent | - |
| dc.publisher.location | 대한민국 | - |
| dc.contributor.assignee | (주)지에스씨알오 | - |
| dc.date.application | 2014-09-17 | - |
| dc.date.registration | 2016-05-09 | - |
| dc.type.iprs | 특허 | - |
| dc.identifier.patentRegistrationNumber | 10-1621162 | - |
| dc.identifier.patentApplicationNumber | 10-2014-0123868 | - |
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Collections - College of Pharmacy > Department of Pharmacy > 4. Patents
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Related Researcher
- Lee, Kyeong
- College of Pharmacy (Department of Pharmacy)