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Cited 35 time in webofscience Cited 37 time in scopus
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Flavonoids and arylbenzofurans from the rhizomes and roots of Sophora tonkinensis with IL-6 production inhibitory activity

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dc.contributor.authorYoo, Hunseung-
dc.contributor.authorChae, Hee-Sung-
dc.contributor.authorKim, Young-Mi-
dc.contributor.authorKang, Minseok-
dc.contributor.authorRyu, Keun Ho-
dc.contributor.authorAhn, Hee Chul-
dc.contributor.authorYoon, Kee Dong-
dc.contributor.authorChin, Young-Won-
dc.contributor.authorKim, Jinwoong-
dc.date.accessioned2024-09-25T03:31:29Z-
dc.date.available2024-09-25T03:31:29Z-
dc.date.issued2014-12-15-
dc.identifier.issn0960-894X-
dc.identifier.issn1464-3405-
dc.identifier.urihttps://scholarworks.dongguk.edu/handle/sw.dongguk/23615-
dc.description.abstractThree new compounds (1-3) and 20 known compounds were isolated from the rhizomes and roots of Sophora tonkinensis, and all the isolates were tested for their inhibitory activity against IL-6 production in HMC-1 cells stimulated by PMA plus ionophore, A23187. Of the tested compounds, compounds 1, 5, 9, and 21 were found to potently inhibit IL-6 production with IC50 values of 1.62, 0.73, 3.01, and 4.02 mu M, respectively. (C) 2014 Elsevier Ltd. All rights reserved.-
dc.format.extent4-
dc.language영어-
dc.language.isoENG-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.titleFlavonoids and arylbenzofurans from the rhizomes and roots of Sophora tonkinensis with IL-6 production inhibitory activity-
dc.typeArticle-
dc.publisher.location영국-
dc.identifier.doi10.1016/j.bmcl.2014.10.077-
dc.identifier.scopusid2-s2.0-84911928389-
dc.identifier.wosid000345581300020-
dc.identifier.bibliographicCitationBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.24, no.24, pp 5644 - 5647-
dc.citation.titleBIOORGANIC & MEDICINAL CHEMISTRY LETTERS-
dc.citation.volume24-
dc.citation.number24-
dc.citation.startPage5644-
dc.citation.endPage5647-
dc.type.docTypeArticle-
dc.description.isOpenAccessN-
dc.description.journalRegisteredClasssci-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Organic-
dc.subject.keywordPlusGLYCYRRHIZA-URALENSIS-
dc.subject.keywordPlusCONSTITUENTS-
dc.subject.keywordPlusALKALOIDS-
dc.subject.keywordAuthorSophora tonkinensis-
dc.subject.keywordAuthorFlavonoid-
dc.subject.keywordAuthorArylbenzofruran-
dc.subject.keywordAuthorInterleukin-6-
dc.subject.keywordAuthorAnti-allergy-
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