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Poly(norepinephrine): Ultrasmooth Material-Independent Surface Chemistry and Nanodepot for Nitric Oxide
- Authors
- Hong, Seonki; Kim, Jihoon; Na, Yun Suk; Park, Junghong; Kim, Sunjin; Singha, Kaushik; Im, Gun-Il; Han, Dong-Keun; Kim, Won Jong; Lee, Haeshin
- Issue Date
- 26-Aug-2013
- Publisher
- WILEY-V C H VERLAG GMBH
- Keywords
- drug delivery; bioinspired chemistry; nitric oxide; polymers; surface chemistry
- Citation
- ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v.52, no.35, pp 9187 - 9191
- Pages
- 5
- Indexed
- SCI
SCIE
SCOPUS
- Journal Title
- ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Volume
- 52
- Number
- 35
- Start Page
- 9187
- End Page
- 9191
- ISSN
- 1433-7851
1521-3773
- Abstract
- Capture and release: The material-independent surface chemistry of a poly(norepinephrine) (pNE) which exhibits perfect smoothness at the nanometer scale is controlled by 3,4-dihydroxybenzaldehyde-norepinephrine (DHBA-NE) conjugates. The pNE layer containing DHBA-NE serves to store and release small therapeutics such as nitric oxide. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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Related Researcher
- Im, Gun Il
- Graduate School (Department of Medicine)