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A novel indole derivative, 2-{3-[1-(benzylsulfonyl)piperidin-4-yl]-2-methyl-1H-indol-1-yl}-1-(pyrrolidin-1-yl)ethenone, suppresses hedgehog signaling and drug-resistant tumor growthopen access

Jung, Joo Hyun; Lee, Hwayoung; Jeon, Jiyeon; Lee, Yoon Ji; Nada, Hossam; Kim, Minkyoung; Lee, Hankyu; Bhattarai, Deepak; Lee, Kyeong; Ko, Hyuk Wan

ArticleIssue Date2024CitationArchiv der Pharmazie, v.357, no.10, pp 1 - 18PublisherWILEY-V C H VERLAG GMBH
SCIESCOPUS
c-KIT Small Molecule Inhibitors as a Therapeutic Strategy for Melanoma: Clinical Insights, SAR, and Future Directionsopen access

Rivonker, Shubham C.; Nada, Hossam; Cho, Jaemin; Kwon, Yong-jun; Lee, Kyeong

ArticleIssue Date2025CitationArchiv der Pharmazie, v.358, no.10PublisherWiley-VCH GmbH
SCIESCOPUS
Chalcone-based benzenesulfonamides as potent and selective inhibitors for human carbonic anhydrase II: Design, synthesis, in vitro, and in silico studies

Lee, Hwa Young; Elkamhawy, Ahmed; Al-Karmalawy, Ahmed A.; Nada, Hossam; Giovannuzzi, Simone; Supuran, Claudiu T.; Lee, Kyeong

ArticleIssue Date2024CitationArchiv der Pharmazie, v.357, no.11, pp 1 - 9PublisherWiley-VCH GmbH
SCIESCOPUS
Chemical induction of the interaction between AIMP2-DX2 and Siah1 to enhance ubiquitination

Kim, Dae Gyu; Kim, Minkyoung; Goo, Ja-il; Kong, Jiwon; Harmalkar, Dipesh S.; Lu, Qili; Sivaraman, Aneesh; Nada, Hossam; Godesi, Sreenivasulu; Lee, Hwayoung, et al.

ArticleIssue Date2024CitationCell Chemical Biology, v.31, no.11, pp 1958 - 1968.e8PublisherCell Press
SCIESCOPUS
From pixels to druggable leads: A CADD strategy for the design and synthesis of potent DDR1 inhibitors

Nada, Hossam; Kim, Sungdo; Jaemin, Cho; Park, Suin; Choi, Yongseok; Lee, Moo Yeol; Lee, Kyeong

ArticleIssue Date2024CitationComputer Methods and Programs in Biomedicine, v.254, pp 1 - 10PublisherElsevier BV
SCIESCOPUS
LMT2368 (1-(4-Chlorophenyl)-3-(3-fluoro-5-(trifluoromethyl)phenyl)urea) Negatively Regulates Inflammation by Inhibiting NLRP3 Inflammasome Activationopen access

Nguyen, Thai Uy; Kwon, Su Jeong; Hurh, Sunghoon; Kale, Ashok; Cho, Jae Min; Nada, Hossam; Kim, Chang Seong; Induvadana, Peela; Park, Beom Jin; Lee, Kyeong, et al.

ArticleIssue Date2025CitationPharmaceutics, v.17, no.10, pp 1 - 20PublisherMDPI
SCIESCOPUS
New insights into protein-protein interaction modulators in drug discovery and therapeutic advanceopen access

Nada, Hossam; Choi, Yongseok; Kim, Sungdo; Kwon, Su Jeong; Meanwell, Nicholas A.; Lee, Kyeong

ArticleIssue Date2024CitationSignal Transduction and Targeted Therapy, v.9, no.1, pp 1 - 32PublisherSPRINGER NATURE
SCIESCOPUS
PT-Finder: A multi-modal neural network approach to target identification

Nada, Hossam; Kim, Sungdo; Lee, Kyeong

ArticleIssue Date2024CitationComputers in Biology and Medicine, v.174, pp 1 - 9PublisherElsevier Ltd
SCIESCOPUS
Quinoxaline-based UCHL5 inhibitor as a next-generation proteasome-targeting anticancer agent beyond 20S inhibitionopen access

Han, Tae-Hee; Lee, Joohan; Im, Joo-Young; Nada, Hossam; Godesi, Sreenivasulu; Kim, Changseong; Seo, Areum; Hwang, Inseo; Shin, Seong-Ah; Lee, Ga Seul, et al.

ArticleIssue Date2026CitationJournal of Advanced ResearchPublisherElsevier B.V.
SCIESCOPUS
Small Molecules in Parkinson's Disease Therapy: From Dopamine Pathways to New Emerging Targetsopen access

Lee, Hwayoung; Elkamhawy, Ahmed; Rakhalskaya, Polina; Lu, Qili; Nada, Hossam; Quan, Guofeng; Lee, Kyeong

ArticleIssue Date2024CitationPharmaceuticals, v.17, no.12, pp 1 - 20PublisherMDPI
SCIESCOPUS
Targeting breast cancer with rationally designed quinazolines: A scaffold hopping strategy

Lee, Kwanshik; Nada, Hossam; Gul, Anam Rana; Elkamhawy, Ahmed; Al-Karmalawy, Ahmed A.; Park, Tae Jung; Lee, Kyeong; Choi, Yongseok

ArticleIssue Date2024CitationJournal of Molecular Structure, v.1315, pp 1 - 12PublisherElsevier BV
강력한 DDR1 억제제의 합성

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